By T. H. Crook III Ph.D., G. J. Larrabee (auth.), Prof. Dr. Lüder Deecke, Prof. Dr. Peter Dal-Bianco (eds.)
The papers compiled during this supplementum are a variety of the simplest con th tributions awarded on the 19 Central-European Neurological Symposium (CNS 19) hung on June 29 - July 1, 1989 in Vienna. the most subject of this convention was once degenerative and age-associated neurological ailments. In fresh many years existence expectancy has dramatically elevated, not less than within the industrialized international locations. This has resulted in severe distortions of the so-called inhabitants pyramids that not appear like such yet start to virtually resemble cylinders. by reason of this "overaging" of the inhabitants, ailments which are linked to age became even more universal than sooner than. It used to be hence greater than average to commit a congress of the CNS sequence to those vital neurological illnesses. the subsequent fields of curiosity are lined: Age-associated reminiscence impairment (AAMI), Alzheimer's and different dementias, Parkinson's affliction and different move problems, stroke and others. in regards to the de males tias, a few papers take care of analysis making use of neuro-imaging equipment resembling MRI, CT, puppy and SPECT, others utilizing electrophysiological equipment. a tremendous point within the early preclinical prognosis of dementia is the inclusion of neuropsychological checks to augment the opportunity of effec tive early therapy. additionally medications which are now lower than medical research are mentioned and initial effects are presented.
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Extra info for Age-associated Neurological Diseases
Acta Psychiatr Scand 81: 551-553 Fischer P, Marterer A, Danielczyk W (1990b) Right-left disorientation in dementia of the Alzheimer's type. Neurology 40: 1619-1620 Fischer P, Simanyi M, Danielczyk W (1990c) Depression in dementia of the Alzheimer type and in Multi-Infarct dementia. Am J Psychiatry 147: 1484-1487 (1907) Miliare Nekrosen mit drusigen Wucherungen der Neurofibrillen, eine Fischer regelmal3ige Veranderung der Hirnrinde bei seniler Demenz. Mschr Psychiat Neurol 22: 361-372 Fitch N, Becker R, Heller A (1988) The inheritance of Alzheimer's disease: a new interpretation.
Br J Psychiatry 114: 797-811 Bleuler E (1916) Lehrbuch der Psychiatrie. Springer, Berlin Boller F, Lopez OL, Moossy J (1989) Diagnosis of dementia: clinicopathologic correlations. Neurology 38: 76-79 Brink TL, Yesavage JA, Lum 0, Heersema PH, Adey M, Rose TL (1982) Screening tests for geriatric depression. Clin Gerontol 1: 37-43 Burns A, Philpot MP, Costa DC, Ell PJ, Levy R (1989) The investigation of Alzheimer's disease with single photon emission tomography. J Neurol Neurosurg Psychiatry 52: 248-253 Caine ED (1981) Pseudodementia.
Immunocytochemically Rosenthal fibers react with antibodies against GF AP and ubiquitin, but do not contain epitopes of MAP1, MAP2 or tau or of NF. It is thus suggested that GFAP/ubiquitin complexes are a major component of Rosenthal fibers. 32 F. Seitelberger et a1. Other inclusions: In Marinesco bodies ubiquitin can be found, although it does, however, not appear to be associated with cytoskeletal proteins. Interestingly, also Corpora amylacea, aging products of glial cells, contain ubiquitin.
Age-associated Neurological Diseases by T. H. Crook III Ph.D., G. J. Larrabee (auth.), Prof. Dr. Lüder Deecke, Prof. Dr. Peter Dal-Bianco (eds.)