By Craig Meyers
One of crucial elements of AIDS is the lack of protecting immune functionality within the contaminated host which ends up in elevated occurrence of opportunistic infections and cancers. This e-book particularly addresses viral-induced human cancers linked to AIDS and saw within the AIDS inhabitants. It addresses the categorical therapy required during this specific inhabitants and the molecular biology of the causative viral agents.
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Extra resources for AIDS-Associated Viral Oncogenesis (Cancer Treatment and Research)
9%. 001). 004). 001). 012). In addition,The Swiss cohort study76 with 6,636 HIV-infected individuals found the incidence of systemic NHL post-HAART to be 4 cases/1,000 p-y. 2. AIDS Malignancies 29 However, other studies found nonsignificant increases in AIDS-related NHL incidence. 2). 5 cases/1,000 p-y post-HAART (p-value not significant). 86,87 The IPI includes clinical features that reflect the growth and invasive potential of the tumor (tumor stage, serum LDH level, and number of extranodal disease sites), the patient’s response to the tumor (performance status), and the patient’s ability to tolerate Table 3.
AIDS MALIGNANCIES ANITA ARORA, MD*, ELIZABETH CHIAO, MD*, AND STEPHEN K. TYRING, MD, PHD† * † Center for Clinical Studies, Houston,TX University of Texas Health Science Center, Houston,TX INTRODUCTION Malignancies were one of the earliest recognized manifestations that lead to the eventual description of the acquired immune deficiency syndrome (AIDS) epidemic. Kaposi’s sarcoma (KS), a rare skin cancer primarily seen in elderly men prior to the epidemic, became one of the first entities described in association with AIDS.
55,56 BL and DLBCL will be discussed separately in the following sections. 57,58 AIDS-related BL are further discussed in this chapter. Table 2. AIDS-related lymphomas (WHO classification)54 Lymphomas also occurring in immunocompetent patients Burkitt’s lymphoma DLBCL: centroblastic, immunoblastic, and anaplastic variants Lymphomas occurring more specifically in HIV-infected patients Primary effusion lymphoma Plasmablastic lymphoma Lymphomas also occurring in other immunodeficiency states Polymorphic or post-transplant lymphoproliferative disorder-like B-cell lymphoma 2.
AIDS-Associated Viral Oncogenesis (Cancer Treatment and Research) by Craig Meyers