Get Amphioxus immunity : tracing the origins of human immunity PDF

By An-Long Xu

ISBN-10: 0128096470

ISBN-13: 9780128096475

ISBN-10: 0128499036

ISBN-13: 9780128499030

Amphioxus Immunity: Tracing the foundation of Human Immunity covers a notable diversity of data approximately Amphioxus and its evolutionary context. This compilation of what's presently recognized approximately Amphioxus, with a pointy concentrate on its immune approach, contains thirteen themes, such as:

  • Amphioxus as a version for figuring out the evolution of vertebrates
  • basic wisdom of immunology
  • immune organs and cells of amphioxus
  • a genomic and transcriptomic view of the Amphioxus immunity
  • pattern reputation method in Amphioxus
  • transcription elements in Amphioxus
  • the supplement method of Amphioxus
  • the oxidative burst method in Amphioxus
  • immune effectors in Amphioxus
  • lipid signaling of immune reaction in Amphioxus
  • apoptosis in amphioxus; primitive adaptive immune procedure of Amphioxus
  • and destiny learn directions

This beneficial reference booklet is loaded with details that might be valuable for somebody who needs to benefit extra concerning the foundation of vertebrates and adaptive immunity.

  • Provides new facts at the starting place of the adaptive immune process, the evolution of innate immunity, and evolution-stage particular immune protection mechanisms
  • Not purely provides the cells and molecules enthusiastic about the adaptive immune reaction in Amphioxus, but additionally characterizes the origination and evolution of the gene households and pathways eager about innate immunity
  • Includes a lot pioneering paintings, from the molecular, genomic, and mobile to the person level

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2008). In contrast, most host transcripts are masked by a 7-methyl-­guanosine ­capping (mRNA) or removed by processing in the maturation process (tRNA and rRNA). , 2008). , 2014). After the recognition of RNA by RIG-I or MDA5, a complex signaling downstream pathway is activated. , 2005), localizes in the mitochondrial outer membrane and serves as a critical signaling adaptor for RIG-I/MDA5. IPS-1 is composed of an N-terminal CARD domain, by which it interacts with an RIG-I or MDA5 CARD domain.

2002. Immunology, fifth ed. W. H. Freeman, New York. , 2009. Endogenous ligands for C-type lectin receptors: the true regulators of immune homeostasis. Immunol. Rev. 230, 22–37. , 2007. Structure and function of Toll receptors and their ligands. Annu. Rev. Biochem. 76, 141–165. , 2009. Signalling through C-type lectin receptors: shaping immune responses. Nat. Rev. Immunol. 9, 465–479. , 1988. The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein.

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Amphioxus immunity : tracing the origins of human immunity by An-Long Xu

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