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After a century of study, a number of traces of facts now point out that the power of adenosine to at once keep watch over inflammatory cells has a massive impression at the services of the inflammatory and immune structures. for that reason, many promising healing ways are commencing to emerge that concentrate on the modulation of adenosine, together with the improvement of compounds that intrude with the breakdown of adenosine, in addition to particular agonists and antagonists of assorted adenosine subtypes.
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Extra info for Annual Review of Immunology Volume 15 1997
Virol. 62:4499–509 Marriott SJ, Boros I, Duvall JF, Brady JN. 1989. Indirect binding of human T-cell leukemia virus type I tax1 to a responsive element in the viral long terminal repeat. Mol. Cell Biol. 9:4152–60 Perini G, Wagner S, Green MR. 1995. Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax. Nature 376:602–5 Baranger AM, Palmer CR, Hamm MK, Giebler HA, Brauweiler A, Nyborg JK, Schepartz A. 1995. Mechanism of DNAbinding enhancement by the human T-cell leukaemia virus transactivator Tax.
Cancer 60:554–61 Tatewaki M, Yamaguchi K, Matsuoka M, Ishii T, Miyasaka M, Mori S, Takatsuki K, Watanabe T. 1995. Constitutive overexpression of the L-selectin gene in fresh leukemic cells of adult T-cell leukemia that can be transactivated by HTLV-I Tax. Blood 86:3109–17 Paterson DJ, Jefferies WA, Green JR, Brandon MR, Corthesy P, Puklavec M, Williams AF. 1987. Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts. Mol. Immunol. 24:1281–90 Mallett S, Fossum S, Barclay AN.
For personal use only. A HISTORY OF H-Y 43 in vitro with antigen (17). This approach was used to generate H-Y-specific CTL from female C57BL/10 mice (an H-2b , H-Y responder strain) immunized by intraperitoneal injection of syngeneic male spleen cells or by skin grafting. Primary mixed lymphocyte culture (MLC) using splenic T cells from unimmunized female mice failed to generate H-Y-specific CTL, but CTL that killed concanavalin A splenic blasts from C57BL/10 male but not female mice were obtained from secondary MLC using spleen cells from immunized females.
Annual Review of Immunology Volume 15 1997 by Annual Reviews